Antidepressants May Be No More Effective Than Placebo: But What About St. John’s Wort and Other Herbal Medicines?

When going thru hell, keep going.” Winston Churchill

Depression is one of the most common mental illnesses and can affect anyone at any age. Characterized by anhedonia (the inability to feel pleasure), despair, and pessimism, depression has high morbidity and recurrence.[1] Overall, more than 50% of the general population in middle- and high-income countries will suffer from at least one mental disorder at some point in their lives. This is obviously a major public health problem with significant consequences for society.[2] We need clear guidelines as to what does and doesn’t work for treating depression.

Continue reading “Antidepressants May Be No More Effective Than Placebo: But What About St. John’s Wort and Other Herbal Medicines?”