Category: Healing Medicine

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Understanding Neutrophil to Lymphocyte Ratio (Part 2): Research Demonstrating its Role as a Valuable Prognostic Marker in Cancer

Understanding Neutrophil to Lymphocyte Ratio (Part 2): Research Demonstrating its Role as a Valuable Prognostic Marker in Cancer

A large body of research (as well as my clinical observations) point to chronic inflammation as a powerful force in the initiation, growth, and spread of cancer. As a result, an essential component of my protocol for health includes addressing inflammation.

As I discussed in part 1 of this series, there are three points to consider when evaluating the role of inflammation in cancer. First, a chronic inflammatory state can initiate cancer development. Second, it’s important to discover and address the root cause of the inflammation—for example, pathogenic (chronic infection), life-style, stress, and/or poor dietary habits. And third, recognize that the cancer itself creates inflammation—as the cancer energy mutates and gains intelligence, it manipulates the immune system, creating a pro-inflammatory micro-environment favorable to cancer growth.

Research indicates that the systemic manifestations of inflammation can provide a valuable biomarker for prognosis and treatment stratification. In particular, numerous studies indicate that a simple indicator of systemic inflammation—based on neutrophilia and/or lymphocytopenia—can provide prognostic information in a wide range of cancer types. In particular, the value of one index (the dNLR) derived from total white cell and neutrophil counts, is enabling large retrospective studies to be carried out.

Neutrophil to Lymphocyte Ratio May Be a Predictor of Mortality in All Conditions

White blood cell (WBC) count is one of the useful inflammatory biomarkers in clinical practice. For example, even if WBC is within normal range, subtypes of WBC including N/L ratio may predict cardiovascular mortality.

N/L ratio is a readily measurable laboratory marker used to evaluate systemic inflammation. There are many different conditions that can affect N/L ratio, including hypertension, diabetes mellitus, metabolic syndrome (1), left ventricular dysfunction, acute coronary syndromes, valvular heart disease, abnormal thyroid function tests, renal or hepatic dysfunction, known malignancy (2,3,4), local or systemic infection, previous history of infection (<3 months), inflammatory diseases, and any medication related to inflammatory conditions.

Here’s one example of how the N/L ratio can be useful as part of the evaluation of a specific cancer and the treatment protocol: not only N/L ratio but also mean platelet volume, red cell distribution width (5), platelet distribution width, CRP, uric acid and gamma-glutamyl transferase (6) are easy markers to evaluate the prognosis of colon cancer patients (7). However, one should keep in mind that N/L ratio itself alone without other inflammatory markers may not give exact information to clinicians about the prognosis of colon cancer patients. (8,9).

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‘Misrepresentation of ‘Integrative Oncology’ in the Literature: Clearing up Misperceptions and Recognizing the Validity of Herbal Medicine at the Forefront of ‘Unified Medicine’

I recently read a paper entitled “Integrative Oncology” 1 published in a peer-reviewed medical journal. To say I was shocked at the misrepresentation presented as “fact” is an understatement.

I am strongly compelled to offer a rebuttal to this article. I can only hope that those who most need the perspective of someone who has worked in clinical practice with cancer patients on a daily basis for almost three decades will benefit from my experience.

Personally, I prefer to use the term “Unified Medicine” over “Integrative Oncology” to more appropriately describe the wholistic ETMS (Eclectic Triphasic Medical System) model I developed and practice, known as ‘Mederi Medicine’ or ‘Mederi Care’.

Mederi Medicine is an approach where all aspects of an individual are addressed for optimal health and well being. This includes the fundamental building blocks of nutrition, herbs, lifestyle, and spiritual and emotional health, with the tools of modern conventional medicine employed when necessary. As a musician, I think of Mederi Medicine as similar to the way that the various parts of an orchestra each play an essential role in creating beautiful music. The ETMS is not a fragmented approach, but is synergistic, meaning that the whole is greater than the sum of its parts. This harmonious approach is something that is sorely lacking in modern conventional medicine”.

 

“I think of Mederi Medicine as similar to the way that the various parts of an orchestra each play an essential role in creating beautiful music”

What’s Wrong with the “Integrative Oncology” Paper?

Honestly, when I first saw the title “Integrative Oncology” I felt hopeful. I thought perhaps this paper would offer helpful information to those suffering from cancer, or to those who dedicate their lives to working with people with cancer. Instead, I found bias, misrepresentation, and outright twisting of the facts and outcomes of studies. This paper clearly states that it has been peer-reviewed, but given the many errors, I find that difficult to believe.

I find it strange that the subtext delineates “integrative approaches (e.g., lifestyle, meditation, yoga, acupuncture, massage)” but overlooks botanical and nutritional medicines, which are widely used as adjunct therapies in cancer protocols. I have no idea what the underlying agenda is in this paper. Why would scientifically and clinically proven modalities be dismissed or overlooked when they offer the potential for help without harm? Continue reading “‘Misrepresentation of ‘Integrative Oncology’ in the Literature: Clearing up Misperceptions and Recognizing the Validity of Herbal Medicine at the Forefront of ‘Unified Medicine’”

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Connecting the Dots in Adrenal-Thyroid Health (Part 3 of 3)

In my two previous posts on these health, I discussed the potential problems associated with diagnosing and treating them. As I stated in my first post, thyroid problems are frequently under diagnosed, primarily because of inadequate testing and incomplete understanding of the complexities of thyroid function. At the same time, they are often treated in ways that further compromise function.

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Natural Strategies to Maximize Thyroid Function (Part 2 of 3)

In my post last week, I introduced the topic of thyroid health and the many misconceptions that the medical profession has about diagnosing and treating thyroid disease. In general, thyroid problems are under diagnosed because the standard blood tests used to evaluate function are woefully inadequate. At the same time, an underactive thyroid is often over treated with thyroid replacement hormones—which frequently cause even greater dysfunction. In my experience, a much more effective approach is to focus on the factors that underlie the dysfunction, providing the support needed to restore balance and function to an endocrine system that has gone awry.

Unfortunately, conventional “modern” medicine insists on viewing the thyroid as an independent entity, and treats any dysfunction by addressing only the thyroid. But in fact, the thyroid sits at the epicenter of the endocrine system and oversees the critical job of regulating the body’s metabolism. Although the thyroid gland weighs less than one ounce, the hormones it produces affect virtually every cell in the body.

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How to Assess Thyroid Health (Part 1 of 3)

While over 20 million people are currently being treated for clinical and subclinical hypothyroidism, there may be as many as 13 million more Americans suffering the ill effects of an undiagnosed thyroid problem–making it one of the most under-diagnosed health conditions in the United States. At the same time, because the thyroid is intimately intertwined with the other glands of the endocrine system, supplementing with thyroid hormones may be counterproductive if the problem is rooted in adrenal fatigue, dietary and lifestyle factors, and stress. Many factors affect thyroid health, including common stressors such as inadequate sleep, exposure to environmental toxins, or minor illnesses. Even the normal physiological changes associated with aging are stressors that are detrimental to thyroid function.

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How To Nourish Vital Spirit: The ETMS Approach

In my blog post last week, I explored the connection between Vital Spirit and health. In my professional work as an herbalist and in my personal life, I believe that a strong and resilient Vital Spirit is the foundation for a healthy and happy life. But how do we strengthen the intangible quality of Vital Spirit? The answer lies in practices that encourage peace, expansiveness, and self-reflection—prayer, meditation, spiritual reading, time in nature, and even creative pursuits where the superficial falls away, and we find our deeper selves. Through these practices, we can be certain that we are living in accordance with our deepest truth.

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