Inflammation is an essential part of our body’s immune defense. When we encounter pathogens such as bacteria, viruses, or parasites, our body responds with inflammation to fight the invaders and increase immune response. In these instances, inflammation is beneficial. But inflammation has a dark side—left unchecked, it can wreak havoc on cells, tissues, and organs. For example, it’s well established that chronic inflammation is a powerful force in the initiation, growth, and spread of cancer.

There are three essential points to consider: First, a chronic inflammatory state can, over time, initiate cancer development. Second, we still need to find the cause of the chronic state of inflammation—for example, pathogenic (chronic infection), life-style, stress, years of poor eating, or a combination of the above. And third, it is important to keep in mind that the cancer energy, as it gains in intelligence, manipulates our immune system, creating a cancer-favorable, pro-inflammatory micro-environment.

Research indicates that the systemic manifestations of inflammation can provide a valuable biomarker for prognosis and treatment stratification. Numerous studies indicate that a simple indicator of systemic inflammation—based on neutrophilia and/or lymphocytopenia—can provide prognostic information in a wide range of cancer types. In particular, the value of one index (the dNLR) derived from total white cell and neutrophil counts, is enabling large retrospective studies to be carried out.

Although not informative from a biological standpoint in distinguishing cause from effect, the results of these studies are likely to be of significance in how we approach cancer. In my practice, I always consider the role of inflammation in cancer and tailor protocols for patients accordingly. The following markers are among those I consider most important:

  • Tumor-associated neutrophils (TANs)
    Bio-Markers: CD11b+, CD66b+, CD63+

Tumor-associated neutrophils (TAN) play a major role in cancer biology. Neutrophils are the most abundant circulating leukocyte in humans, and are phenotypically plastic. Neutrophils, as a key component in inflammation, often play a crucial role in inflammation driven tumorigenesis. TAN can take an anti-tumorigenic (what we are calling an “N1-phenotype”) versus a pro-tumorigenic (“N2”) phenotype. The anti-tumor activities of N1 TANs include expression of more immuno-activating cytokines and chemokines, lower levels of arginase, and more capability of killing tumor cells. N2 neutrophils are pro-tumorigenic, and secrete T2 cytokines.


read more

Baking cookies and sharing them with friends is part of our family’s holiday tradition. This year, I created a new recipe that I’d like to share with you. It’s a delicious holiday treat (made with spelt, walnuts, and other healthy ingredients) that I hope you’ll enjoy as much as we do!

Ingredients:

  • 4 oz butter (1 stick butter)
  • 2 oz coconut oil
  • 1 ½ teaspoon vanilla

    Walnut-Coconut Crescent Holiday Cookies

  • ½ cup maple syrup
  • 1/3 cup coconut sugar
  • 1 cup oat flour
  • 1 cup sprouted spelt flour *
  • ½ cup Pamela’s baking mix
  • ½ teaspoon sea salt
  • 1 ½ cups chopped walnuts*
  • 1 cup shredded coconut, toasted on stove for 2 minutes, stirring frequently

Sugar and spice topping:

  • 1 tsp. cinnamon
  • 1/8 tsp. cardamom
  • 2 tsp. maple sugar
  • 1 tsp. coconut milk powder

Instructions:

  1. Soften butter and mix with coconut oil and vanilla. Beat in maple syrup and coconut sugar.
  2. Sift oat flour, spelt flour, baking mix, and sea salt and add to wet ingredients.
  3. Fold in chopped walnuts and coconut.
  4. Shape into crescents and refrigerate for at least 1 hour before baking.
  5. Preheat oven to 350 degrees F convection.
  6. Bake cookies for 20-25 minutes, or until golden brown.
  7. Remove from oven, place on rack to cool, and using a sifter, dust cookies with the sugar and spice mixture.

read more

I recently read a paper entitled “Integrative Oncology” 1 published in a peer-reviewed medical journal. To say I was shocked at the misrepresentation presented as “fact” is an understatement.

I am strongly compelled to offer a rebuttal to this article. I can only hope that those who most need the perspective of someone who has worked in clinical practice with cancer patients on a daily basis for almost three decades will benefit from my experience.

Personally, I prefer to use the term “Unified Medicine” over “Integrative Oncology” to more appropriately describe the wholistic ETMS (Eclectic Triphasic Medical System) model I developed and practice, known as ‘Mederi Medicine’ or ‘Mederi Care’.

Mederi Medicine is an approach where all aspects of an individual are addressed for optimal health and well being. This includes the fundamental building blocks of nutrition, herbs, lifestyle, and spiritual and emotional health, with the tools of modern conventional medicine employed when necessary. As a musician, I think of Mederi Medicine as similar to the way that the various parts of an orchestra each play an essential role in creating beautiful music. The ETMS is not a fragmented approach, but is synergistic, meaning that the whole is greater than the sum of its parts. This harmonious approach is something that is sorely lacking in modern conventional medicine”.

 

“I think of Mederi Medicine as similar to the way that the various parts of an orchestra each play an essential role in creating beautiful music”

What’s Wrong with the “Integrative Oncology” Paper?

Honestly, when I first saw the title “Integrative Oncology” I felt hopeful. I thought perhaps this paper would offer helpful information to those suffering from cancer, or to those who dedicate their lives to working with people with cancer. Instead, I found bias, misrepresentation, and outright twisting of the facts and outcomes of studies. This paper clearly states that it has been peer-reviewed, but given the many errors, I find that difficult to believe.

I find it strange that the subtext delineates “integrative approaches (e.g., lifestyle, meditation, yoga, acupuncture, massage)” but overlooks botanical and nutritional medicines, which are widely used as adjunct therapies in cancer protocols. I have no idea what the underlying agenda is in this paper. Why would scientifically and clinically proven modalities be dismissed or overlooked when they offer the potential for help without harm?


read more

music-health

The Greek lyrical poet Archilochus said, “We don’t rise to the level of our expectations, we fall to the level of our training.”

This quote suggests that the ability to succeed is not based on chance, nor can someone expect to succeed based solely on his or her innate abilities. Success instead is the result of training in a focused manner, so that when faced with a critical situation, a reaction occurs without conscious thought—essentially, it has become an instinctual response born of dedicated practice.

The saying can also be interpreted in a broader fashion, reflecting one’s ability to change and to “push the envelope,” as great jazz musicians do. Basketball, my favorite sport, shares some similarities in approach. The combination of talent and training, with some scripted aspects of play and the freedom for spontaneous improvisation is the ultimate in team synergy. When played in this way, basketball is beautiful. The unscripted nature of the game is similar to the improvisational nature of jazz, in which the notes are often unknown in advance, and rely on the combination of thought (intelligence) and feeling response (heart).


read more

In my last post, I broadly discussed the exciting field of epigenetics, which is radically changing the landscape of what we’ve long believed about genetics and biological destiny. Emerging research shows that food and herbs may be the most important factors in our genetic well-being, directly affecting our health, disease risk, and longevity.

As a clinical herbalist, I find the relationship between herbs and epigenetics particularly compelling. A large body of research shows that a wide array of botanical compounds work in a variety of ways to maintain health at the cellular level, and offer great promise in improving our molecular expression, protecting against cellular stressors and aging by normalizing gene behavior. We cannot change the genes we have, but we can positively alter the fate and behavior of our genes by supplying them with beneficial herbal and dietary compounds.

shutterstock_134698571.0


read more

I believe zinc deficiency might be the number one overlooked health concern facing our aging population. Zinc is an essential trace element found in every cell of your body, where it plays an important role in cellular structure, function, and metabolism. A multi-tasking mineral, zinc is required for metabolic health, immune response, reproductive health, and numerous biochemical functions. Zinc also helps preserve DNA integrity, is vital for more than 2000 transcription factors, is necessary for the production of brain neurotransmitters, and functions as an antioxidant and anti-inflammatory agent.


read more